Each year, the Cancer Research Society awards two-year grants to support some of the most innovative cancer research projects.

This year, we are very proud to award 70 new grants worth $8.8 million.

Three of these grants were awarded through our Scholarship for the Next Generation of Scientists (SNGS) competition, a funding program with the goal of supporting the future generation of Canadian researchers. In addition, on the occasion of the Society's 75th anniversary, five Young Investigators, who have distinguished themselves by the exceptional quality of their work, will receive special 75th Anniversary grants having a higher stipend.

The Cancer Research Society will also continue to fund all grants and research projects awarded in previous years. Therefore, the Society is very proud to fund more than 150 projects dedicated to cancer research worth $12.6 million in this pandemic year.

As our recent campaign reminds us, ‘’Cancer does not take a break’’ and this is why the Cancer Research Society remains committed to investing 100% of the funds raised to support research.

List of 2020 Grant Recipients

In May and June 2020, the Society held seven evaluation committee meetings, composed of more than 100 researchers and clinicians from across the country, to review the research projects.

Causes and prevention - the most effective approach to reducing the risk of developing the disease

Christian Baron

Université de Montréal – funded in partnership with the Fondation Bergeron-Jetté Fund

Development of lead molecules for the prevention of cancer caused by Helicobacter pylori.

Jean-François Côté

Montreal Clinical Research Institute (IRCM), Université de Montréal – funded in partnership with the Quebec Breast Cancer Foundation

Uncovering regulators of breast cancer dormancy.

Shokrollah Elahi

University of Alberta – funded in partnership with the Canadian Institutes of Health Research

CD71+ erythroid cells impair tumour immunogenicity and promote tumour progression.

Gerardo Ferbeyre

Université de Montréal – funded in partnership with the Charlotte Légaré Memorial Fund

Senescent macrophages promote pancreatic tumorigenesis: a link between cancer and aging.

Vincent Giguère

McGill University – funded in partnership with Génome Québec

Transcriptional activity of the NuRD complex in prostate cancer.

Vikki Ho

Research Center of CHUM – funded in partnership with the Environment-Cancer FundTM of the Cancer Research Society and Read for the Cure

The influence of occupational and genetic risk factors in breast cancer etiology.

Tae-Hee Kim

The Hospital for Sick Children

Defining the mechanisms of lineage plasticity in intestinal tumorigenesis.

Peter K Kim

The Hospital for Sick Children

Role of Peroxisomes in Renal Cell Carcinoma Tumorigenesis.

Darryl Leong

McMaster University – funded in partnership with the Environment-Cancer FundTM of the Cancer Research Society and Read for the Cure

International Cancer Epidemiology (ICE) Study.

Ivan Litvinov

McGill University Health Centre Research Institute – funded in partnership with the Canadian Institutes of Health Research

Studying the biology and clinical utility of aberrantly expressed testicular cancer and embryonic stem cell genes for the treatment of advanced or recurrent non-melanoma skin cancers (NMSCs).

Marco Magalhaes

University of Toronto

Investigating TNFR1 signaling in invadopodia formation and malignant transformation of oral cancer.

Kirk McManus

University of Manitoba – funded in partnership with Ovarian Cancer Canada

Exploring and exploiting aberrant RBX1 expression in high-grade serous ovarian cancer.

Christopher Moraes

McGill University – funded in partnership with the Canadian Institutes of Health Research

Targeting changes in tissue stiffness regulated by neutrophil-derived exosomes as a promoter of breast cancer liver metastasis.

William Muller

Rosalind and Morris Goodman Cancer Research Centre, McGill University – funded in partnership with CURE Foundation

The role of an alternative ErbB2 splice isoform in breast cancer progression.

Christiaan Righolt

University of Manitoba – funded in partnership with the Canadian Institutes of Health Research

Use of glycogen synthase kinase-3β inhibitors (GSK3Is) and prostate cancer risk and prognosis.

Manuela Santos

Université de Montréal Hospital Centre Research Centre

Postoperative intestinal healing and anastomotic colorectal cancer recurrence and metastasis.

Joseph Torchia

University of Western Ontario

The role of farnesoid X-receptor and bile acid signaling in liver carcinogenesis.

Alan Underhill

University of Alberta – funded in partnership with the Canadian Institutes of Health Research

Phase separation and epigenome reprogramming in cancer.

Jim Uniacke

University of Guelph – funded in partnership with CURE Foundation

Hypoxic cancer cells coordinate cell adhesion and invasion decisions via cadherin-22.

Detection – early detection is critical to improving patient outcomes

Francois Benard

BC Cancer, part of the Provincial Health Services Authority – funded in partnership with the Herbert James Davies Memorial Fund

Development of CXCR4-targeting fluorescent radiotheranostic agents via a novel cross-linking macrocyclization strategy.

Robert Britton

Simon Fraser University

18F-Fluorinated amino acids as PET radiotracers for multiple myeloma.

Benjamin K. Tsang

Ottawa Hospital Research Institute

Plasma gelsolin as a biomarker for early diagnosis of ovarian cancer & chemo- responsiveness, as well as a predictor of residual disease & patient survival.

Treatment – the development of new treatments, including targeted or personalized therapies

Rebecca Auer

Ottawa Hospital Research Institute

Investigating the role of impaired mTOR signaling in the loss of NK cell effector functions in cancer patients following surgical stress.

Christian Beauséjour

Research Centre of the Sainte-Justine University Hospital

Impact of a senescent stromal environment on the tumor immune response.

Byram Bridle

University of Guelph

Advancing a promising infected cancer cell vaccine platform into the translational research pipeline.

Apostolos Christopoulos

Centre Hospitalier de l'Université de Montréal

Targeting autophagy in combination treatment for head and neck squamous cell carcinoma.

Javier Clemente-Casares

University of Alberta – funded in partnership with the Canadian Institutes of Health Research

Transcriptional requirements for pro-cachectic monocytic and granulocytic myeloid-derived suppressor cells (gMDSC) amplification.

Shoukat Dedhar

BC Cancer, part of the Provincial Health Services Authority

Overcoming cancer recurrence and metastatic progression by targeting "anastasis".

Sonia Victoria del Rincon

Lady Davis Institute for Medical Research, Jewish General Hospital – funded in partnership with the Canadian Institutes of Health Research

Aberrant MNK1/2 signaling as a mechanism involved in breast cancer liver metastasis.

Fred Dick

Western University

Netrin signaling in dormant ovarian cancer cell survival.

Lorenzo Ferri

Research Institute of the McGill University Health Center – funded in partnership with the Aristotle Fund

Identifying mechanisms and salvage therapies for chemoresistance in microsatellite unstable gastro-esophageal adenocarcinoma.

David Granville

University of British Columbia

Granzyme B: A Novel Target for the Treatment of Radiodermatitis.

Jean-Philippe Gratton

Université de Montréal

Role of ZO-1 in endothelial cell biology and in tumor angiogenesis.

Kevin Hay

BC Cancer, part of the Provincial Health Services Authority – funded in partnership with the Herbert James Davies Memorial Fund

Novel multiple myeloma target identification by cell surface proteomics for chimeric antigen receptor T-cell (CAR T-cell) immunotherapy.

Michiru Hirasawa

Memorial University

Role of hypothalamic neuropeptides in metabolic effects of cancer.

Nada Jabado

Research Institute of the McGill University Health Centre – funded in partnership with Génome Québec

Understanding the impact of H3.3 G34 mutations on childhood brain tumors.

Arezu Jahani-Asl

Lady Davis Institute for Medical Research, Jewish General Hospital – funded in partnership with the Canadian Institutes of Health Research

LGALS1 regulation of glioblastoma tumorigenesis.

Courtney Jones

University Health Network

Targeting energy production in leukemia stem cells.

Jean-Philippe Lambert

Université Laval – funded in partnership with Génome Québec

Using BET bromodomain inhibitors to create phenotypic lethality in melanoma.

Bruno Larrivée

Université de Montréal

Characterization of the effects of vascular normalization on the tumor microenvironment.

Josée N Lavoie

Research Center of the CHU de Québec-Université Laval

Deciphering mechanical stress-induced nuclear envelope remodeling in tumour cells.

Cheng-Han Lee

BC Cancer, part of the Provincial Health Services Authority – funded in partnership with the Ann Matyas Memorial Fund

Therapeutic screening of patient tumour-derived malignant mixed Müllerian tumour (MMMT) disease models.

Benjamin Lok

University Health Network

Employing small cell lung cancer patient-derived organoid cultures as an efficient high-throughput strategy to identify novel therapeutic approaches.

Honglin Luo

University of British Columbia – funded in partnership with the Katherine Campbell MacDonald Memorial Fund

Novel oncolytic virus for lung cancer treatment.

Paola Marcato

Dalhousie University

Identification of novel mediators of paclitaxel response in breast cancer for improving treatment efficacy.

Sylvain Meloche

Institute for Research in Immunology and Cancer of the Université de Montréal (IRIC)

Role of ERK3 MAP kinase signaling in triple-negative breast cancer progression and metastasis.

Tarik Moroy

Montreal Clinical Research Institute (IRCM), Université de Montréal

Role of the DDX3X RNA helicase in Burkitt lymphoma.

Bhushan Nagar

McGill University

Protein phosphatase PPM1G regulates colorectal cancer cells survival and migration by targeting eIF4E phosphorylation.

Hanne Ostergaard

University of Alberta

Contribution of the hematopoietic cytoskeletal adaptor protein leupaxin to the immune response to cancer.

Jerry Pelletier

McGill University

Manipulating the process of translation termination to uncloak tumor cells.

Silvia Penuela

Western University

Targeting PANX1 channels as a new strategy to reduce growth and angiogenesis of aggressive gliomas.

Janusz Rak

Research Institute of the McGill University Health Centre – funded in partnership with Génome Québec

Exosomal representation of new vulnerabilities induced in glioma stem cells by therapy.

Jüri Reimand

Ontario Institute for Cancer Research – funded in partnership with the Canadian Institutes of Health Research

Systematic study of regional mutation rates in multiple cancer types to identify the role of chemotherapies in metastasis.

Stefan Reinsberg

University of British Columbia – funded in partnership with the Charlotte Légaré Memorial Fund

Development of OEMRI as a biomarker for hypoxia in pancreatic cancer.

Philippe Roux

Université de Montréal – funded in partnership with the Katherine Campbell MacDonald Memorial Fund

Copper bioavailability as a new vulnerability in colorectal cancer.

Ralf Schirrmacher

University of Alberta

Development of heparanase radioligands for tumour imaging and staging.

Woong-Kyung Suh

Montreal Clinical Research Institute (IRCM), Université de Montréal

Role of SLAMF7 in immune surveillance of AITL, a germinal center-derived T cell lymphoma.

Nehalkumar Thakor

University of Lethbridge

Regulation of mRNA translation by eIF5B in glioblastoma.

Sandra Turcotte

Université de Moncton – funded in partnership with Canadian VHL Alliance

Harnessing autophagy and lysosomes as a potential therapeutic approach in hereditary renal cell carcinoma with von Hippel-Lindau disease.

Brian C. Wilson

University Health Network

Upregulation of immune response to reduce tumour progression and metastasis of melanoma using photodynamic therapy.

Ryan Wylie

McMaster University

Multi-Antigen T cell Engagers (MATEs) for targeting cancer heterogeneity.

Wei Zhang

University of Guelph

Targeting RFWD3-RPA interaction to modulate DNA interstrand crosslink repair.

Recipients of the Scholarship for the Next Generation of Scientists (SNGS)

Sampath Kumar Loganathan

Sinai Health System

Part 1 : In vivo CRISPR to study tumor suppressors in Head and Neck Squamous Cell Carcinoma (HNSCC)
Part 2 : An in vivo CRISPR screen of G-Protein coupled receptors to identify drug targets in Head and Neck Cancer.

Elena Kuzmin

McGill University

Part 1 : Evolution of large copy number variants in breast cancer through genetic network rewiring
Part 2 : Systematic mapping of genetic vulnerabilities of large chromosomal deletions in triple negative breast cancer.

Liis Uuskula-Reimand

The Hospital for Sick Children

Part 1 : Understanding functions of type II topoisomerases in chromatin architecture regulation and transcription using auxin-inducible degron system
Part 2 : Dissecting the functional role of topoisomerase associated non-coding mutations in hepatocellular carcinoma.

Recipients of the Special 75th Anniversary grants

Sheela Abraham

Queen's University

Interrogating extracellular signalling factors involved in the development of chronic myeloid leukaemia (CML).

Dalia Barsyte-Lovejoy

University of Toronto

Epigenetic regulator NSD2 in the biology and treatment of multiple myeloma.

Andrew Beharry

University of Toronto

Targeting carboxylesterase 2 to predict and suppress anticancer drug resistance in pancreatic cancer.

Geneviève Deblois

Université de Montréal

Investigating the contribution of alpha-ketoglutarate in the modulation of chromatin landscapes in triple-negative breast cancer.

Laura Hulea

Centre de Recherche de l'Hopital Maisonneuve-Rosemont, Université de Montréal

Metabolic vulnerabilities in pediatric acute megakaryoblastic leukemia.

The financial support provided by the Cancer Research Society is made possible thanks to the generosity of thousands of donors, but also to partners who co-fund certain grants.

  • Ann Matyas Memorial Fund
  • Aristotle Fund
  • Charlotte Légaré Memorial Fund
  • Fondation Bergeron-Jetté
  • Herbert James Davies Memorial Fund
  • Katherine Campbell MacDonald Memorial Fund
  • The Cancer Research Society's Environment-Cancer FundMC funded in part by Read for the Cure
  • Canadian Institutes of Health Research
  • Canadian VHL Alliance
  • CURE Foundation
  • Génome Québec
  • Ovarian Cancer Canada
  • Quebec Breast Cancer Foundation

Altum - Proposal Central: the new online grant management system

The Society wishes to inform the scientific community that researchers will now be able to submit their grant applications more easily and efficiently through the use of a new online grant management system. The launch of the 2021 Operating Grants competition and the call for proposals will be online, starting November 16, 2020.

Again, we thank our donors and partners warmly for their support.

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